THE DEFINITIVE GUIDE TO PAZOPANIB

Steer clear of coadministration of pazopanib with powerful CYP3A4 inhibitors if possible; if should coadminister, decrease pazopanib dose to 400 mg/dayMinor (1)dasatinib and pazopanib each boost QTc interval. Minor/Importance Not known.nifedipine will raise the amount or influence of pazopanib by affecting hepatic/intestinal enzyme CYP3A4 metabolis